Walk-in Research Scientist Analytical @ Ahmedabad
Time and Venue
17th November , 10.00 AM - 5.00 PM
Four Points by Sheraton Ahmedabad Opposite Gujarat College, Ellis Bridge, Ahmedabad, Gujarat 380006, India
Contact - Deepanshu Bhatt (8696900583)
Strategic
- Actively imbibing the values and philosophy of PI Industries.
- Efficient contribution to the overall success of product innovation (PRI) through scientific contribution to objectives and targets being set by the leadership team.
- Fullfilling requirements and achieveing goals set by the Team Leader and Group Leader
- Working as a team member, contributing to the team objective with special focus on achiving and exceeding the set target.
- Development of individual & team strengths by attending trainings based on the regular feedback as an individual and as a team
Operational
- Monitoring reaction masses using LCMS/GCMS.
- Execution of purity assessment and assay determination of samples using GC/HPLC/UFLC.
- Able to carry method development for challenging compounds through GC/GCMS/HPLC/UFLC
- Developing methods on Prep HPLC for purification/isolation of impure compounds.
- Elucidating and confirming structures using NMR, FTIR and LCMS/MS
- Ensure the scheduled performance of calibrations, Preventive maintenance and troubleshooting of core analytical instrument.
- Following the set instrument maintenance practices like periodic solvent changes, system flushing, etc.
- Assist the other team members in day to day activities like sample preparation, method developments, report generation and data management.
- Following safety practices with out fail.
Financial
- Planning the activities with existing resources and infra structure.
- Suggesting the cost-effective areas to the Team Leader / Group Leader
- Developing methods to improve the environment safety and to reduce the cost.
People
- Collaborate with team members and cross functional teams to meet research objectives.
- Develop and foster positive relationships with other teams and support groups to maximize cooperation and consequent benefit to objective delivery
- Should be able to work in multitasking environment
- Ensure team harmony through collaboration and active participation in all team discussion
Apart from the above responibilities, specific responsibilities of Research scientists
Note : The Associate would in any of the areas listed below based on the requirement and should have sufficient knowledge and expertise in the area alloted as listed below
1.HPLC/UFLC
- Candidate should be well versed with normal and reverse phase chromatography techniques.
- Able to optimize chromatographic methods
- Keen knowledge on low level analyte-impurities quantification by HPLC.
2.LCMS SQD & TQD
- Well versed with operations of one or more makes of LCMS-SQD & TQD instruments.
- Aware of basic principles related to mass spectrometry, sources, analysers and detectors.
- Hands on experience in analysis of compounds using LCMS instrument and releasing the mass confirmation reports.
- Keen knowledge on ppb / ppm level quantification of analytes from AI, formulations, various matrices like microsomes, soil, plant extracts by LCMSMS.
- Perform possible structural elucidation/Identification of degradants/metabolites/impurities using LCMS/MS
3.NMR
- Perform suitable 1D/2D NMR experiments based on the requirement and confirm one among proposed structures or propose a new structure.
- Manage the NMR activities viz, perform routine NMR (1D&2D) analysis, QNMR, cryogen replenishing.
- Keen knowledge of NMR technology & instrument maintenance.
4.Physchem assays
- Have hands on knowledge of various in vitro ADME/ physchem assays like solubility, LogP, pKa and in vitro Metabolic stability assay.
- Able to develop methods, check method compatibility for accuracy, precision, matrix effect and apply it further for the quantification of formulations, plant extracts, various matrices like soil, microsomes etc.
- Perform the microsomal stability experiments to determine half-life and Clint. Awareness about Met ID using various scans, fragmentation tree & HRMS will be an added advantage.
- Knowledge about sample preparation and analysis of photo stability and hydrolytic stability.
5.Prep-HPLC
- Able to develop a robust chromatographic method both at analytical and preparative scale, by designing cost effective methods for chiral and achiral molecules.
Knowledge of chiral chromatography and isolation of enantiomers using preparative HPLC.
