Performing all ADME assays
Method development and data collection by LC-MS/MS, and other modalities (Absorbance/Fluorescence)
Supporting in new assay development for ADME activities
To analyse data from enzyme activities (GraphPad Prism, MS-excel) & MS data (Sciex)
Compiling reports and interfacing with collaborators
Coordinating with third-party collaborators for PK study (animal models)
Conducting day-to-day testing and profiling of compounds in cells/protein-based assays
Drafting reports, documenting experiments and proficiently presenting results within the lab and in various forums/meetings as and when needed
Work closely with other biology group members involved in screening, cell biology, protein biology and ADME, offering integrated drug discovery support alongside chemistry for multiple client-based projects
Contributing in group activities (like ordering, stocking and follow-ups etc.)
1-4 years of working experience with LC-MS/MS, HPLC, bio-analytical studies etc.
An excellent understanding and knowledge of laboratory tools, techniques, methods, and underlying principles
Hands-on/practical exposure in general biotech laboratory equipment (cell-culture lab, in-vitro and ADME lab)
Excellent theoretical understanding and practical work experience with cell culture techniques (established cell lines), ADME assays (microsomal stability, plasma stability, solubility, permeability, CYP inhibition assays, plasma protein binding assays etc.)
An ability to overcome technical challenges and exercise sound judgment under pressure
High self-motivation to initiate projects and work independently under aggressive deadlines
A strong technical knowledge with exceptional attention to detail
An excellent personal rapport and an ability to engender trust and respect
An ability to work well as part of a small focussed team and build relationships
An ability to multitask, recognize problems and provide input to solutions
An exceptional communication skill and an ease in interaction with all stakeholders
An infectious enthusiasm for life, work and making a difference to the world in which we live
A bright, friendly, flexible personality with agility to switch between different skill sets
An exceptional organisational skill that thrives working in a fast-paced and vibrant team environment
Positivity, focus and a winning mentality allied with kindness
Curiosity, energy, creativity, and bravery with a strong desire to help to build the o2h culture
